A genetic replacement system for selection-based engineering of essential proteins

BACKGROUND: Essential genes represent the core of biological functions required for viability. Molecular understanding of essentiality as well as design of synthetic cellular systems includes the engineering of essential proteins. An impediment to this effort is the lack of growth-based selection sy...

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Detalles Bibliográficos
Autores principales: Billerbeck, Sonja, Panke, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Technical Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503863/
https://www.ncbi.nlm.nih.gov/pubmed/22898007
http://dx.doi.org/10.1186/1475-2859-11-110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503863/
https://www.ncbi.nlm.nih.gov/pubmed/22898007
http://dx.doi.org/10.1186/1475-2859-11-110

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