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A genetic replacement system for selection-based engineering of essential proteins
BACKGROUND: Essential genes represent the core of biological functions required for viability. Molecular understanding of essentiality as well as design of synthetic cellular systems includes the engineering of essential proteins. An impediment to this effort is the lack of growth-based selection sy...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503863/ https://www.ncbi.nlm.nih.gov/pubmed/22898007 http://dx.doi.org/10.1186/1475-2859-11-110 |