Cargando…
Inhibition of the ecto-beta subunit of F1F0-ATPase inhibits proliferation and induces apoptosis in acute myeloid leukemia cell lines
BACKGROUND: Leukemia, a heterogeneous clonal disorder of hematopoietic progenitor cells, presents a world-wide health problem, especially in childhood. F1F0 ATPase, an inner mitochondrial enzyme, is expressed on the plasma membrane of tumor cells, and its inhibition induces both anti-angiogenic and...
Autores principales: | Wen-Li, Zhao, Jian, Wang, Yan-Fang, Tao, Xing, Feng, Yan-Hong, Li, Xue-Ming, Zhu, Min, Zhang, Jian, Ni, Jian, Pan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503881/ https://www.ncbi.nlm.nih.gov/pubmed/23140181 http://dx.doi.org/10.1186/1756-9966-31-92 |
Ejemplares similares
-
ATP synthase ecto-α-subunit: a novel therapeutic target for breast cancer
por: Pan, Jian, et al.
Publicado: (2011) -
ε Subunit of Bacillus subtilis F(1)-ATPase Relieves MgADP Inhibition
por: Mizumoto, Junya, et al.
Publicado: (2013) -
E2F1‑mediated RAB34 upregulation accelerates the proliferation and inhibits the cell cycle arrest and apoptosis of acute myeloid leukemia cells
por: Xiong, Xiaojie, et al.
Publicado: (2023) -
Inhibition of thermophilic F(1)-ATPase by the ε subunit takes different path from the ADP-Mg inhibition
por: Haruyama, Takamitsu, et al.
Publicado: (2010) -
On the history of ecto-ATPases: The role of W. A. Engelhardt
por: Orlov, Sergei N.
Publicado: (2007)