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Inhibition of the ecto-beta subunit of F1F0-ATPase inhibits proliferation and induces apoptosis in acute myeloid leukemia cell lines

BACKGROUND: Leukemia, a heterogeneous clonal disorder of hematopoietic progenitor cells, presents a world-wide health problem, especially in childhood. F1F0 ATPase, an inner mitochondrial enzyme, is expressed on the plasma membrane of tumor cells, and its inhibition induces both anti-angiogenic and...

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Detalles Bibliográficos
Autores principales:	Wen-Li, Zhao, Jian, Wang, Yan-Fang, Tao, Xing, Feng, Yan-Hong, Li, Xue-Ming, Zhu, Min, Zhang, Jian, Ni, Jian, Pan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503881/ https://www.ncbi.nlm.nih.gov/pubmed/23140181 http://dx.doi.org/10.1186/1756-9966-31-92

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