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Identification of Biological Markers of Liver X Receptor (LXR) Activation at the Cell Surface of Human Monocytes
BACKGROUND: Liver X receptor (LXR) α and LXR β (NR1H3 and NR1H2) are oxysterol-activated nuclear receptors involved in the control of major metabolic pathways such as cholesterol homeostasis, lipogenesis, inflammation and innate immunity. Synthetic LXR agonists are currently under development and co...
Autores principales: | Rébé, Cédric, Filomenko, Rodolphe, Raveneau, Magalie, Chevriaux, Angélique, Ishibashi, Minako, Lagrost, Laurent, Junien, Jean Louis, Gambert, Philippe, Masson, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504056/ https://www.ncbi.nlm.nih.gov/pubmed/23185273 http://dx.doi.org/10.1371/journal.pone.0048738 |
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