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Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

A major goal in regenerative medicine is the predictable manipulation of human embryonic stem cells (hESCs) to defined cell fates that faithfully represent their somatic counterparts. Directed differentiation of hESCs into neuronal populations has galvanized much interest into their potential applic...

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Detalles Bibliográficos
Autores principales:	Patani, Rickie, Lewis, Patrick A, Trabzuni, Daniah, Puddifoot, Clare A, Wyllie, David J A, Walker, Robert, Smith, Colin, Hardingham, Giles E, Weale, Michael, Hardy, John, Chandran, Siddharthan, Ryten, Mina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504076/ https://www.ncbi.nlm.nih.gov/pubmed/22681703 http://dx.doi.org/10.1111/j.1471-4159.2012.07825.x

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