MCPIP1 Down-Regulates IL-2 Expression through an ARE-Independent Pathway

IL-2 plays a key role in the survival and proliferation of immune cells, especially T lymphocytes. Its expression is precisely regulated at transcriptional and posttranscriptional level. IL-2 is known to be regulated by RNA binding proteins, such as tristetraprolin (TTP), via an AU-rich element (ARE...

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Detalles Bibliográficos
Autores principales: Li, Min, Cao, Wenqiang, Liu, Haifeng, Zhang, Wei, Liu, Xia, Cai, Zhijian, Guo, Jing, Wang, Xuelian, Hui, Zhaoyuan, Zhang, Hang, Wang, Jianli, Wang, Lie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504106/
https://www.ncbi.nlm.nih.gov/pubmed/23185455
http://dx.doi.org/10.1371/journal.pone.0049841

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