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Silent Damage of Noise on Cochlear Afferent Innervation in Guinea Pigs and the Impact on Temporal Processing
Noise-exposure at levels low enough to avoid a permanent threshold shift has been found to cause a massive, delayed degeneration of spiral ganglion neurons (SGNs) in mouse cochleae. Damage to the afferent innervation was initiated by a loss of synaptic ribbons, which is largely irreversible in mice....
Autores principales: | Liu, Lijie, Wang, Hui, Shi, Lijuan, Almuklass, Awad, He, Tingting, Aiken, Steve, Bance, Manohar, Yin, Shankai, Wang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504112/ https://www.ncbi.nlm.nih.gov/pubmed/23185359 http://dx.doi.org/10.1371/journal.pone.0049550 |
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