Cargando…

Whole-Transcriptome Sequencing Identifies Novel IRF2BP2-CDX1 Fusion Gene Brought about by Translocation t(1;5)(q42;q32) in Mesenchymal Chondrosarcoma

Mesenchymal chondrosarcomas (MCs) account for 3–10% of primary chondrosarcomas. The cytogenetic literature includes only ten such tumours with karyotypic information and no specific aberrations have been identified. Using a purely molecular genetic approach a HEY1-NCOA2 fusion gene was recently dete...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nyquist, Kaja B., Panagopoulos, Ioannis, Thorsen, Jim, Haugom, Lisbeth, Gorunova, Ludmila, Bjerkehagen, Bodil, Fosså, Alexander, Guriby, Marianne, Nome, Torfinn, Lothe, Ragnhild A., Skotheim, Rolf I., Heim, Sverre, Micci, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504151/ https://www.ncbi.nlm.nih.gov/pubmed/23185413 http://dx.doi.org/10.1371/journal.pone.0049705

Ejemplares similares

Fusion of the Genes EWSR1 and PBX3 in Retroperitoneal Leiomyoma with t(9;22)(q33;q12)
por: Panagopoulos, Ioannis, et al.
Publicado: (2015)

Novel KAT6B-KANSL1 Fusion Gene Identified by RNA Sequencing in Retroperitoneal Leiomyoma with t(10;17)(q22;q21)
por: Panagopoulos, Ioannis, et al.
Publicado: (2015)

The “Grep” Command But Not FusionMap, FusionFinder or ChimeraScan Captures the CIC-DUX4 Fusion Gene from Whole Transcriptome Sequencing Data on a Small Round Cell Tumor with t(4;19)(q35;q13)
por: Panagopoulos, Ioannis, et al.
Publicado: (2014)

Molecular characterization of the t(4;12)(q27~28;q14~15) chromosomal rearrangement in lipoma
por: Agostini, Antonio, et al.
Publicado: (2016)

The recurrent chromosomal translocation t(12;18) (q14~15;q12~21) causes the fusion gene HMGA2-SETBP1 and HMGA2 expression in lipoma and osteochondrolipoma
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2015)

Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2014)

Fusion of the TBL1XR1 and HMGA1 genes in splenic hemangioma with t(3;6)(q26;p21)
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2015)

Rearrangement of chromosome bands 12q14~15 causing HMGA2-SOX5 gene fusion and HMGA2 expression in extraskeletal osteochondroma
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2015)

Identification of SETD2-NF1 fusion gene in a pediatric spindle cell tumor with the chromosomal translocation t(3;17)(p21;q12)
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Fusion of the HMGA2 and C9orf92 genes in myolipoma with t(9;12)(p22;q14)
por: Panagopoulos, Ioannis, et al.
Publicado: (2016)

Novel Fusion of MYST/Esa1-Associated Factor 6 and PHF1 in Endometrial Stromal Sarcoma
por: Panagopoulos, Ioannis, et al.
Publicado: (2012)

FAM53B truncation caused by t(10;19)(q26;q13) chromosome translocation in acute lymphoblastic leukemia
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Several fusion genes identified by whole transcriptome sequencing in a spindle cell sarcoma with rearrangements of chromosome arm 12q and MDM2 amplification
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2014)

RNA‐sequencing identifies novel GREB1‐NCOA2 fusion gene in a uterine sarcoma with the chromosomal translocation t(2;8)(p25;q13)
por: Brunetti, Marta, et al.
Publicado: (2017)

Novel CSF1-S100A10 fusion gene and CSF1 transcript identified by RNA sequencing in tenosynovial giant cell tumors
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2014)

Karyotyping and analysis of GNAS locus in intramuscular myxomas
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Myeloid leukemia with t(7;21)(p22;q22) and 5q deletion
por: PANAGOPOULOS, IOANNIS, et al.
Publicado: (2013)

RUNX1-PDCD6 fusion resulting from a novel t(5;21)(p15;q22) chromosome translocation in myelodysplastic syndrome secondary to chronic lymphocytic leukemia
por: Panagopoulos, Ioannis, et al.
Publicado: (2018)

Gene fusions AHRR-NCOA2, NCOA2-ETV4, ETV4-AHRR, P4HA2-TBCK, and TBCK-P4HA2 resulting from the translocations t(5;8;17)(p15;q13;q21) and t(4;5)(q24;q31) in a soft tissue angiofibroma
por: Panagopoulos, Ioannis, et al.
Publicado: (2016)

High-throughput sequencing identifies an NFIA/CBFA2T3 fusion gene in acute erythroid leukemia with t(1;16)(p31;q24)
por: Micci, F, et al.
Publicado: (2013)

Loss of chromosome 13 material in cellular angiofibromas indicates pathogenetic similarity with spindle cell lipomas
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
por: Gorunova, Ludmila, et al.
Publicado: (2022)

PAN3–PSMA2 fusion resulting from a novel t(7;13)(p14;q12) chromosome translocation in a myelodysplastic syndrome that evolved into acute myeloid leukemia
por: Panagopoulos, Ioannis, et al.
Publicado: (2018)

Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)
por: Torkildsen, Synne, et al.
Publicado: (2015)

Tumor Spreading to the Contralateral Ovary in Bilateral Ovarian Carcinoma Is a Late Event in Clonal Evolution
por: Micci, Francesca, et al.
Publicado: (2010)

RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
por: Panagopoulos, Ioannis, et al.
Publicado: (2016)

Fusion of ZMYND8 and RELA Genes in Acute Erythroid Leukemia
por: Panagopoulos, Ioannis, et al.
Publicado: (2013)

Genetic heterogeneity in leiomyomas of deep soft tissue
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Genomic characterization of ependymomas reveals 6q loss as the most common aberration
por: OLSEN, THALE KRISTIN, et al.
Publicado: (2014)

Identification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma
por: Brunetti, Marta, et al.
Publicado: (2018)

Loss of 11p11 is a frequent and early event in sporadic nonfunctioning pancreatic neuroendocrine neoplasms
por: HAUGVIK, SVEN-PETTER, et al.
Publicado: (2014)

Genomic aberrations in borderline ovarian tumors
por: Micci, Francesca, et al.
Publicado: (2010)

Bilateral ovarian carcinomas differ in the expression of metastasis-related genes
por: Smebye, Marianne Lislerud, et al.
Publicado: (2017)

Fusion of the genes ataxin 2 like, ATXN2L, and Janus kinase 2, JAK2, in cutaneous CD4 positive T-cell lymphoma
por: Panagopoulos, Ioannis, et al.
Publicado: (2017)

Novel RNA variants in colorectal cancers
por: Hoff, Andreas M., et al.
Publicado: (2015)

Fusion of the genes BRD8 and PHF1 in endometrial stromal sarcoma
por: Micci, Francesca, et al.
Publicado: (2017)

Cytogenetic and molecular profile of endometrial stromal sarcoma
por: Micci, Francesca, et al.
Publicado: (2016)

Low Frequency of ESRRA–C11orf20 Fusion Gene in Ovarian Carcinomas
por: Micci, Francesca, et al.
Publicado: (2014)

A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
por: Skotheim, Rolf I, et al.
Publicado: (2009)

Molecular pathogenesis and prognostication of "low‐grade'' and "high‐grade" endometrial stromal sarcoma
por: Micci, Francesca, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_mk4qom7odc5lt98u27j22sjb4a