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Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations
BACKGROUND: Concern has recently emerged regarding the safety of natural health products (NHPs)–therapies that are increasingly recommended by various health providers, including conventional physicians. Recognizing that most individuals in the Western world now consume vitamins and many take herbal...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504157/ https://www.ncbi.nlm.nih.gov/pubmed/23185404 http://dx.doi.org/10.1371/journal.pone.0049676 |
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author | Genuis, Stephen J. Schwalfenberg, Gerry Siy, Anna-Kristen J. Rodushkin, Ilya |
author_facet | Genuis, Stephen J. Schwalfenberg, Gerry Siy, Anna-Kristen J. Rodushkin, Ilya |
author_sort | Genuis, Stephen J. |
collection | PubMed |
description | BACKGROUND: Concern has recently emerged regarding the safety of natural health products (NHPs)–therapies that are increasingly recommended by various health providers, including conventional physicians. Recognizing that most individuals in the Western world now consume vitamins and many take herbal agents, this study endeavored to determine levels of toxic element contamination within a range of NHPs. METHODS: Toxic element testing was performed on 121 NHPs (including Ayurvedic, traditional Chinese, and various marine-source products) as well as 49 routinely prescribed pharmaceutical preparations. Testing was also performed on several batches of one prenatal supplement, with multiple samples tested within each batch. Results were compared to existing toxicant regulatory limits. RESULTS: Toxic element contamination was found in many supplements and pharmaceuticals; levels exceeding established limits were only found in a small percentage of the NHPs tested and none of the drugs tested. Some NHPs demonstrated contamination levels above preferred daily endpoints for mercury, cadmium, lead, arsenic or aluminum. NHPs manufactured in China generally had higher levels of mercury and aluminum. CONCLUSIONS: Exposure to toxic elements is occurring regularly as a result of some contaminated NHPs. Best practices for quality control–developed and implemented by the NHP industry with government oversight–is recommended to guard the safety of unsuspecting consumers. |
format | Online Article Text |
id | pubmed-3504157 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-35041572012-11-26 Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations Genuis, Stephen J. Schwalfenberg, Gerry Siy, Anna-Kristen J. Rodushkin, Ilya PLoS One Research Article BACKGROUND: Concern has recently emerged regarding the safety of natural health products (NHPs)–therapies that are increasingly recommended by various health providers, including conventional physicians. Recognizing that most individuals in the Western world now consume vitamins and many take herbal agents, this study endeavored to determine levels of toxic element contamination within a range of NHPs. METHODS: Toxic element testing was performed on 121 NHPs (including Ayurvedic, traditional Chinese, and various marine-source products) as well as 49 routinely prescribed pharmaceutical preparations. Testing was also performed on several batches of one prenatal supplement, with multiple samples tested within each batch. Results were compared to existing toxicant regulatory limits. RESULTS: Toxic element contamination was found in many supplements and pharmaceuticals; levels exceeding established limits were only found in a small percentage of the NHPs tested and none of the drugs tested. Some NHPs demonstrated contamination levels above preferred daily endpoints for mercury, cadmium, lead, arsenic or aluminum. NHPs manufactured in China generally had higher levels of mercury and aluminum. CONCLUSIONS: Exposure to toxic elements is occurring regularly as a result of some contaminated NHPs. Best practices for quality control–developed and implemented by the NHP industry with government oversight–is recommended to guard the safety of unsuspecting consumers. Public Library of Science 2012-11-21 /pmc/articles/PMC3504157/ /pubmed/23185404 http://dx.doi.org/10.1371/journal.pone.0049676 Text en © 2012 Genuis et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Genuis, Stephen J. Schwalfenberg, Gerry Siy, Anna-Kristen J. Rodushkin, Ilya Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations |
title | Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations |
title_full | Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations |
title_fullStr | Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations |
title_full_unstemmed | Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations |
title_short | Toxic Element Contamination of Natural Health Products and Pharmaceutical Preparations |
title_sort | toxic element contamination of natural health products and pharmaceutical preparations |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504157/ https://www.ncbi.nlm.nih.gov/pubmed/23185404 http://dx.doi.org/10.1371/journal.pone.0049676 |
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