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Is There a Role for HTLV-1-Specific CTL in Adult T-Cell Leukemia/Lymphoma?
ATLL is an aggressive malignancy of T cells that affects about 5% of individuals infected with HTLV-1. The precise mechanism of oncogenesis is not known, but there is evidence that two regulatory viral proteins, Tax and HBZ, are involved. A high set point proviral load is associated with development...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504207/ https://www.ncbi.nlm.nih.gov/pubmed/23259066 http://dx.doi.org/10.1155/2012/391953 |