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Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells

We demonstrate that convergent transcription induces transcriptional gene silencing (TGS) in trans for both fission yeast and mammalian cells. This methodology has advantages over existing strategies to induce gene silencing. Previous studies in fission yeast have characterized TGS as a cis specific...

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Detalles Bibliográficos
Autores principales:	Gullerova, Monika, Proudfoot, Nick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504457/ https://www.ncbi.nlm.nih.gov/pubmed/23022730 http://dx.doi.org/10.1038/nsmb.2392

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