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Spectral pattern of urinary water as a biomarker of estrus in the giant panda

Near infrared spectroscopy (NIRS) has been successfully used for non-invasive diagnosis of diseases and abnormalities where water spectral patterns are found to play an important role. The present study investigates water absorbance patterns indicative of estrus in the female giant panda. NIR spectr...

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Autores principales: Kinoshita, Kodzue, Miyazaki, Mari, Morita, Hiroyuki, Vassileva, Maria, Tang, Chunxiang, Li, Desheng, Ishikawa, Osamu, Kusunoki, Hiroshi, Tsenkova, Roumiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504474/
https://www.ncbi.nlm.nih.gov/pubmed/23181188
http://dx.doi.org/10.1038/srep00856
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author Kinoshita, Kodzue
Miyazaki, Mari
Morita, Hiroyuki
Vassileva, Maria
Tang, Chunxiang
Li, Desheng
Ishikawa, Osamu
Kusunoki, Hiroshi
Tsenkova, Roumiana
author_facet Kinoshita, Kodzue
Miyazaki, Mari
Morita, Hiroyuki
Vassileva, Maria
Tang, Chunxiang
Li, Desheng
Ishikawa, Osamu
Kusunoki, Hiroshi
Tsenkova, Roumiana
author_sort Kinoshita, Kodzue
collection PubMed
description Near infrared spectroscopy (NIRS) has been successfully used for non-invasive diagnosis of diseases and abnormalities where water spectral patterns are found to play an important role. The present study investigates water absorbance patterns indicative of estrus in the female giant panda. NIR spectra of urine samples were acquired from the same animal on a daily basis over three consecutive putative estrus periods. Characteristic water absorbance patterns based on 12 specific water absorbance bands were discovered, which displayed high urine spectral variation, suggesting that hydrogen-bonded water structures increase with estrus. Regression analysis of urine spectra and spectra of estrone-3-glucuronide standard concentrations at these water bands showed high correlation with estrogen levels. Cluster analysis of urine spectra grouped together estrus samples from different years. These results open a new avenue for using water structure as a molecular mirror for fast estrus detection.
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spelling pubmed-35044742012-11-23 Spectral pattern of urinary water as a biomarker of estrus in the giant panda Kinoshita, Kodzue Miyazaki, Mari Morita, Hiroyuki Vassileva, Maria Tang, Chunxiang Li, Desheng Ishikawa, Osamu Kusunoki, Hiroshi Tsenkova, Roumiana Sci Rep Article Near infrared spectroscopy (NIRS) has been successfully used for non-invasive diagnosis of diseases and abnormalities where water spectral patterns are found to play an important role. The present study investigates water absorbance patterns indicative of estrus in the female giant panda. NIR spectra of urine samples were acquired from the same animal on a daily basis over three consecutive putative estrus periods. Characteristic water absorbance patterns based on 12 specific water absorbance bands were discovered, which displayed high urine spectral variation, suggesting that hydrogen-bonded water structures increase with estrus. Regression analysis of urine spectra and spectra of estrone-3-glucuronide standard concentrations at these water bands showed high correlation with estrogen levels. Cluster analysis of urine spectra grouped together estrus samples from different years. These results open a new avenue for using water structure as a molecular mirror for fast estrus detection. Nature Publishing Group 2012-11-22 /pmc/articles/PMC3504474/ /pubmed/23181188 http://dx.doi.org/10.1038/srep00856 Text en Copyright © 2012, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Article
Kinoshita, Kodzue
Miyazaki, Mari
Morita, Hiroyuki
Vassileva, Maria
Tang, Chunxiang
Li, Desheng
Ishikawa, Osamu
Kusunoki, Hiroshi
Tsenkova, Roumiana
Spectral pattern of urinary water as a biomarker of estrus in the giant panda
title Spectral pattern of urinary water as a biomarker of estrus in the giant panda
title_full Spectral pattern of urinary water as a biomarker of estrus in the giant panda
title_fullStr Spectral pattern of urinary water as a biomarker of estrus in the giant panda
title_full_unstemmed Spectral pattern of urinary water as a biomarker of estrus in the giant panda
title_short Spectral pattern of urinary water as a biomarker of estrus in the giant panda
title_sort spectral pattern of urinary water as a biomarker of estrus in the giant panda
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504474/
https://www.ncbi.nlm.nih.gov/pubmed/23181188
http://dx.doi.org/10.1038/srep00856
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