Mitochondrial Atpif1 regulates heme synthesis in developing erythroblasts

Defects in the availability of heme substrates or the catalytic activity of the terminal enzyme in heme biosynthesis, ferrochelatase (Fech), impair heme synthesis, and thus cause human congenital anemias(1,2). The inter-dependent functions of regulators of mitochondrial homeostasis and enzymes respo...

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Detalles Bibliográficos
Autores principales: Shah, Dhvanit I., Takahashi-Makise, Naoko, Cooney, Jeffrey D., Li, Liangtao, Schultz, Iman J., Pierce, Eric L., Narla, Anupama, Seguin, Alexandra, Hattangadi, Shilpa M., Medlock, Amy E., Langer, Nathaniel B., Dailey, Tamara A., Hurst, Slater N., Faccenda, Danilo, Wiwczar, Jessica M., Heggers, Spencer K., Vogin, Guillaume, Chen, Wen, Chen, Caiyong, Campagna, Dean R., Brugnara, Carlo, Zhou, Yi, Ebert, Benjamin L., Danial, Nika N., Fleming, Mark D., Ward, Diane M., Campanella, Michelangelo, Dailey, Harry A., Kaplan, Jerry, Paw, Barry H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504625/
https://www.ncbi.nlm.nih.gov/pubmed/23135403
http://dx.doi.org/10.1038/nature11536

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