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BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs

The differentiation of several T and B cell effector programs in the immune system is directed by signature transcription factors that induce rapid epigenetic remodeling. We report that PLZF, the BTB-ZF transcription factor directing the innate-like effector program of NKT thymocytes (1,2) was promi...

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Detalles Bibliográficos
Autores principales: Mathew, Rebecca, Seiler, Michael P., Scanlon, Seth T., Mao, Aiping, Constantinides, Michael G., Bertozzi-Villa, Clara, Singer, Jeffrey D., Bendelac, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504649/
https://www.ncbi.nlm.nih.gov/pubmed/23086144
http://dx.doi.org/10.1038/nature11548