Metagenomic analysis: the challenge of the data bonanza

Several thousand metagenomes have already been sequenced, and this number is set to grow rapidly in the forthcoming years as the uptake of high-throughput sequencing technologies continues. Hand-in-hand with this data bonanza comes the computationally overwhelming task of analysis. Herein, we descri...

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Detalles Bibliográficos
Autores principales: Hunter, Chris I., Mitchell, Alex, Jones, Philip, McAnulla, Craig, Pesseat, Sebastien, Scheremetjew, Maxim, Hunter, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504930/
https://www.ncbi.nlm.nih.gov/pubmed/22962339
http://dx.doi.org/10.1093/bib/bbs020
Descripción
Sumario:Several thousand metagenomes have already been sequenced, and this number is set to grow rapidly in the forthcoming years as the uptake of high-throughput sequencing technologies continues. Hand-in-hand with this data bonanza comes the computationally overwhelming task of analysis. Herein, we describe some of the bioinformatic approaches currently used by metagenomics researchers to analyze their data, the issues they face and the steps that could be taken to help overcome these challenges.

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