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Association of transcobalamin c. 776C>G with overall survival in patients with primary central nervous system lymphoma

BACKGROUND: Chemotherapy for primary central nervous system lymphoma (PCNSL) is based on methotrexate (MTX), which interferes with both nucleic acid synthesis and methionine metabolism. We have reported previously that genetic variants with influence on methionine metabolism are associated with MTX...

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Detalles Bibliográficos
Autores principales: Linnebank, M, Moskau, S, Kowoll, A, Semmler, A, Bangard, C, Vogt-Schaden, M, Egerer, G, Schackert, G, Reichmann, H, Schmidt-Wolf, I G H, Pels, H, Schlegel, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504945/
https://www.ncbi.nlm.nih.gov/pubmed/23099805
http://dx.doi.org/10.1038/bjc.2012.476