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Association of transcobalamin c. 776C>G with overall survival in patients with primary central nervous system lymphoma
BACKGROUND: Chemotherapy for primary central nervous system lymphoma (PCNSL) is based on methotrexate (MTX), which interferes with both nucleic acid synthesis and methionine metabolism. We have reported previously that genetic variants with influence on methionine metabolism are associated with MTX...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504945/ https://www.ncbi.nlm.nih.gov/pubmed/23099805 http://dx.doi.org/10.1038/bjc.2012.476 |