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EGFR and K-ras gene mutation status in squamous cell anal carcinoma: a role for concurrent radiation and EGFR inhibitors?

BACKGROUND: There is a growing appreciation for radio-sensitiser use in multi-modal cancer treatment models. Squamous cell anal carcinoma (SCAC) is a rare gastrointestinal tumour traditionally treated with concurrent chemotherapy and radiation. Cetuximab, an epidermal growth factor receptor (EGFR) i...

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Detalles Bibliográficos
Autores principales:	Paliga, A, Onerheim, R, Gologan, A, Chong, G, Spatz, A, Niazi, T, Garant, A, Macheto, D, Alcindor, T, Vuong, T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504953/ https://www.ncbi.nlm.nih.gov/pubmed/23093229 http://dx.doi.org/10.1038/bjc.2012.479

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