Cystic kidney diseases: many ways to form a cyst

Renal cysts are a common radiological finding in both adults and children. They occur in a variety of conditions, and the clinical presentation, management, and prognosis varies widely. In this article, we discuss the major causes of renal cysts in children and adults with a particular focus on the...

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Detalles Bibliográficos
Autores principales: Loftus, Hannah, Ong, Albert C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Educational Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505496/
https://www.ncbi.nlm.nih.gov/pubmed/22736301
http://dx.doi.org/10.1007/s00467-012-2221-x
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author Loftus, Hannah
Ong, Albert C. M.
author_facet Loftus, Hannah
Ong, Albert C. M.
author_sort Loftus, Hannah
collection PubMed
description Renal cysts are a common radiological finding in both adults and children. They occur in a variety of conditions, and the clinical presentation, management, and prognosis varies widely. In this article, we discuss the major causes of renal cysts in children and adults with a particular focus on the most common genetic forms. Many cystoproteins have been localized to the cilia centrosome complex (CCC). We consider the evidence for a universal ‘cilia hypothesis’ for cyst formation and the evidence for non-ciliary proteins in cyst formation.
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spelling pubmed-35054962012-11-28 Cystic kidney diseases: many ways to form a cyst Loftus, Hannah Ong, Albert C. M. Pediatr Nephrol Educational Review Renal cysts are a common radiological finding in both adults and children. They occur in a variety of conditions, and the clinical presentation, management, and prognosis varies widely. In this article, we discuss the major causes of renal cysts in children and adults with a particular focus on the most common genetic forms. Many cystoproteins have been localized to the cilia centrosome complex (CCC). We consider the evidence for a universal ‘cilia hypothesis’ for cyst formation and the evidence for non-ciliary proteins in cyst formation. Springer-Verlag 2012-06-27 2013-01 /pmc/articles/PMC3505496/ /pubmed/22736301 http://dx.doi.org/10.1007/s00467-012-2221-x Text en © IPNA 2012
spellingShingle Educational Review
Loftus, Hannah
Ong, Albert C. M.
Cystic kidney diseases: many ways to form a cyst
title Cystic kidney diseases: many ways to form a cyst
title_full Cystic kidney diseases: many ways to form a cyst
title_fullStr Cystic kidney diseases: many ways to form a cyst
title_full_unstemmed Cystic kidney diseases: many ways to form a cyst
title_short Cystic kidney diseases: many ways to form a cyst
title_sort cystic kidney diseases: many ways to form a cyst
topic Educational Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505496/
https://www.ncbi.nlm.nih.gov/pubmed/22736301
http://dx.doi.org/10.1007/s00467-012-2221-x
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