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Plasma leptin and neuropeptide Y concentrations in patients with rheumatoid arthritis treated with infliximab, a TNF-α antagonist

TNF-α is one of the key proinflammatory cytokines in pathogenesis of rheumatoid arthritis (RA). TNF-α was also found to enhance synthesis of leptin. Leptin is mainly adipocyte-derived hormone controlling appetite and energy expenditure. It acts through inhibition of neuropeptide Y secretion. It is p...

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Detalles Bibliográficos
Autores principales:	Kopec-Medrek, Magdalena, Kotulska, Anna, Widuchowska, Malgorzata, Adamczak, Marcin, Więcek, Andrzej, Kucharz, Eugene J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505553/ https://www.ncbi.nlm.nih.gov/pubmed/22048440 http://dx.doi.org/10.1007/s00296-011-2182-6

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