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Use of response surface methodology for development of new microwell-based spectrophotometric method for determination of atrovastatin calcium in tablets
BACKGROUND: Response surface methodology by Box–Behnken design employing the multivariate approach enables substantial improvement in the method development using fewer experiments, without wastage of large volumes of organic solvents, which leads to high analysis cost. This methodology has not been...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505740/ https://www.ncbi.nlm.nih.gov/pubmed/23146143 http://dx.doi.org/10.1186/1752-153X-6-134 |