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Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice

BACKGROUND: Obesity is associated with accumulation of macrophages in white adipose tissue (WAT), which contribute to the development of insulin resistance. Germ-free (GF) mice have reduced adiposity and are protected against diet-induced obesity, OBJECTIVE: To investigate whether the gut microbiota...

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Detalles Bibliográficos
Autores principales:	Caesar, Robert, Reigstad, Christopher S, Bäckhed, Helene Kling, Reinhardt, Christoph, Ketonen, Maria, Östergren Lundén, Gunnel, Cani, Patrice D, Bäckhed, Fredrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Group 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505865/ https://www.ncbi.nlm.nih.gov/pubmed/22535377 http://dx.doi.org/10.1136/gutjnl-2011-301689

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