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PKCδ Regulates Translation Initiation through PKR and eIF2α in Response to Retinoic Acid in Acute Myeloid Leukemia Cells

Translation initiation and activity of eukaryotic initiation factor-alpha (eIF2α), the rate-limiting step of translation initiation, is often overactivated in malignant cells. Here, we investigated the regulation and role of eIF2α in acute promyelocytic (APL) and acute myeloid leukemia (AML) cells i...

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Detalles Bibliográficos
Autores principales:	Ozpolat, Bulent, Akar, Ugur, Tekedereli, Ibrahim, Alpay, S. Neslihan, Barria, Magaly, Gezgen, Baki, Zhang, Nianxiang, Coombes, Kevin, Kornblau, Steve, Lopez-Berestein, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505929/ https://www.ncbi.nlm.nih.gov/pubmed/23259068 http://dx.doi.org/10.1155/2012/482905

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