MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders

Common blood disorders include hematopoietic cell malignancies or leukemias and plasma cell dyscrasia, all of which have associated microRNA abnormalities. In this paper, we discuss several leukemias including acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) and identify altered m...

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Autores principales: Yuan, Yao, Kasar, Siddha, Underbayev, Chingiz, Prakash, Sindhuri, Raveche, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505936/
https://www.ncbi.nlm.nih.gov/pubmed/23259069
http://dx.doi.org/10.1155/2012/603830
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author Yuan, Yao
Kasar, Siddha
Underbayev, Chingiz
Prakash, Sindhuri
Raveche, Elizabeth
author_facet Yuan, Yao
Kasar, Siddha
Underbayev, Chingiz
Prakash, Sindhuri
Raveche, Elizabeth
author_sort Yuan, Yao
collection PubMed
description Common blood disorders include hematopoietic cell malignancies or leukemias and plasma cell dyscrasia, all of which have associated microRNA abnormalities. In this paper, we discuss several leukemias including acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) and identify altered microRNAs and their targets. Immune disorders with altered blood levels of antibodies include autoimmune disorders, such as systemic lupus erythematosus (SLE) with associated anti-self-autoantibodies and immunoglobulin A nephropathy (IgAN) also have related microRNA abnormalities. The alterations in microRNAs may serve as therapeutic targets in these blood disorders.
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spelling pubmed-35059362012-12-20 MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders Yuan, Yao Kasar, Siddha Underbayev, Chingiz Prakash, Sindhuri Raveche, Elizabeth Leuk Res Treatment Review Article Common blood disorders include hematopoietic cell malignancies or leukemias and plasma cell dyscrasia, all of which have associated microRNA abnormalities. In this paper, we discuss several leukemias including acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) and identify altered microRNAs and their targets. Immune disorders with altered blood levels of antibodies include autoimmune disorders, such as systemic lupus erythematosus (SLE) with associated anti-self-autoantibodies and immunoglobulin A nephropathy (IgAN) also have related microRNA abnormalities. The alterations in microRNAs may serve as therapeutic targets in these blood disorders. Hindawi Publishing Corporation 2012 2012-06-17 /pmc/articles/PMC3505936/ /pubmed/23259069 http://dx.doi.org/10.1155/2012/603830 Text en Copyright © 2012 Yao Yuan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Yuan, Yao
Kasar, Siddha
Underbayev, Chingiz
Prakash, Sindhuri
Raveche, Elizabeth
MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders
title MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders
title_full MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders
title_fullStr MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders
title_full_unstemmed MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders
title_short MicroRNAs in Acute Myeloid Leukemia and Other Blood Disorders
title_sort micrornas in acute myeloid leukemia and other blood disorders
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505936/
https://www.ncbi.nlm.nih.gov/pubmed/23259069
http://dx.doi.org/10.1155/2012/603830
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