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Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine(†)

8-Nitro-2′-deoxyguanosine (8-nitrodG) is a relatively unstable, mutagenic lesion of DNA that is increasingly believed to be associated with tissue inflammation. Due to the lability of the glycosidic bond, 8-nitrodG cannot be incorporated into oligodeoxynucleotides (ODNs) by chemical DNA synthesis an...

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Detalles Bibliográficos
Autores principales:	Bhamra, Inder, Compagnone-Post, Patricia, O’Neil, Ian A., Iwanejko, Lesley A., Bates, Andrew D., Cosstick, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505964/ https://www.ncbi.nlm.nih.gov/pubmed/22965127 http://dx.doi.org/10.1093/nar/gks799

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