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Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract

Hfq is a post-transcriptional regulator that plays a key role in bacterial gene expression by binding AU-rich sequences and A-tracts to facilitate the annealing of sRNAs to target mRNAs and to affect RNA stability. To understand how Hfq from the Gram-positive bacterium Staphylococcus aureus (Sa) bin...

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Detalles Bibliográficos
Autores principales: Horstmann, Nicola, Orans, Jillian, Valentin-Hansen, Poul, Shelburne, Samuel A., Brennan, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505971/
https://www.ncbi.nlm.nih.gov/pubmed/22965117
http://dx.doi.org/10.1093/nar/gks809

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