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Functional impact bias reveals cancer drivers
Identifying cancer driver genes and pathways among all somatic mutations detected in a cohort of tumors is a key challenge in cancer genomics. Traditionally, this is done by prioritizing genes according to the recurrence of alterations that they bear. However, this approach has some known limitation...
Autores principales: | Gonzalez-Perez, Abel, Lopez-Bigas, Nuria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505979/ https://www.ncbi.nlm.nih.gov/pubmed/22904074 http://dx.doi.org/10.1093/nar/gks743 |
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