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Chromatin signature discovery via histone modification profile alignments

We report on the development of an unsupervised algorithm for the genome-wide discovery and analysis of chromatin signatures. Our Chromatin-profile Alignment followed by Tree-clustering algorithm (ChAT) employs dynamic programming of combinatorial histone modification profiles to identify locally si...

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Detalles Bibliográficos
Autores principales:	Wang, Jianrong, Lunyak, Victoria V., Jordan, I. King
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505981/ https://www.ncbi.nlm.nih.gov/pubmed/22989711 http://dx.doi.org/10.1093/nar/gks848

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