Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient

We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosup...

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Detalles Bibliográficos
Autores principales: Tsukada, Akira, Fujimura, Taku, Furudate, Sadanori, Kambayashi, Yumi, Hashimoto, Akira, Aiba, Setsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Published online: October, 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506065/
https://www.ncbi.nlm.nih.gov/pubmed/23185157
http://dx.doi.org/10.1159/000345095
Descripción
Sumario:We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.

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