Effective modulation of CD4(+)CD25(+high) regulatory T and NK cells in malignant patients by combination of interferon-α and interleukin-2

Overinduced CD4(+)CD25(+high) regulatory T cells (Treg) and downregulated NK cells contribute to tumor-relevant immune tolerance and interfere with tumor immunity. In this study, we aimed to design a novel strategy with cytokine combination to correct the dysregulated Treg and NK cells in malignant...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Guangxian, Yang, Wuwei, Guo, Mei, Liu, Xiaoqing, Huang, Naixiang, Li, Dingfeng, Jiang, Zefei, Yang, Wenfeng, Zhang, Weijing, Su, Hang, Liu, Zhiqing, Liu, Tieqiang, Wang, Dongmei, Huang, Shan, Yao, Bo, Man, Qiuhong, Qiu, Lijuan, Sun, Xuedong, Sun, Yuying, Liu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506201/
https://www.ncbi.nlm.nih.gov/pubmed/22722448
http://dx.doi.org/10.1007/s00262-012-1297-2

Ejemplares similares

Ejemplares similares