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Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity

BACKGROUND: As proinflammatory cytokines seem to play a role in discogenic back pain, substances exhibiting anti-inflammatory effects on intervertebral disc cells may be used as minimal-invasive therapeutics for intradiscal/epidural injection. The purpose of this study was to investigate the anti-in...

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Detalles Bibliográficos
Autores principales: Klawitter, Marina, Quero, Lilian, Klasen, Juergen, Gloess, Alexia N, Klopprogge, Babette, Hausmann, Oliver, Boos, Norbert, Wuertz, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506446/
https://www.ncbi.nlm.nih.gov/pubmed/22909087
http://dx.doi.org/10.1186/1476-9255-9-29

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