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Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity
BACKGROUND: As proinflammatory cytokines seem to play a role in discogenic back pain, substances exhibiting anti-inflammatory effects on intervertebral disc cells may be used as minimal-invasive therapeutics for intradiscal/epidural injection. The purpose of this study was to investigate the anti-in...
Autores principales: | Klawitter, Marina, Quero, Lilian, Klasen, Juergen, Gloess, Alexia N, Klopprogge, Babette, Hausmann, Oliver, Boos, Norbert, Wuertz, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506446/ https://www.ncbi.nlm.nih.gov/pubmed/22909087 http://dx.doi.org/10.1186/1476-9255-9-29 |
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