Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment

BACKGROUND: Culture-negative endocarditis due to Tropheryma whipplei is a rare disease. Mostly the diagnosis is made by histologic examination of resected heart valve tissue. CASE PRESENTATION: In this case report, we described a patient with a classical Whipple’s disease. Transesophageal echocardio...

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Autores principales: Algin, Ahmet, Wegdam-Blans, Marjolijn, Verduin, Kees, Janssen, Hans, van Dantzig, Jan-Melle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506451/
https://www.ncbi.nlm.nih.gov/pubmed/23110725
http://dx.doi.org/10.1186/1756-0500-5-600
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author Algin, Ahmet
Wegdam-Blans, Marjolijn
Verduin, Kees
Janssen, Hans
van Dantzig, Jan-Melle
author_facet Algin, Ahmet
Wegdam-Blans, Marjolijn
Verduin, Kees
Janssen, Hans
van Dantzig, Jan-Melle
author_sort Algin, Ahmet
collection PubMed
description BACKGROUND: Culture-negative endocarditis due to Tropheryma whipplei is a rare disease. Mostly the diagnosis is made by histologic examination of resected heart valve tissue. CASE PRESENTATION: In this case report, we described a patient with a classical Whipple’s disease. Transesophageal echocardiography (TEE) showed a vegetation on noncoronary cusp of the aortic valve. Whipple’s disease was confirmed by positive Tropheryma whipplei polymerase chain reaction (PCR) in EDTA blood and a duodenal biopsy with positive periodic acid-Schiff stain (PAS) macrophages. CONCLUSION: Due to timely diagnosis, our patient was treated with antibiotics without valve replacement.
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spelling pubmed-35064512012-11-27 Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment Algin, Ahmet Wegdam-Blans, Marjolijn Verduin, Kees Janssen, Hans van Dantzig, Jan-Melle BMC Res Notes Case Report BACKGROUND: Culture-negative endocarditis due to Tropheryma whipplei is a rare disease. Mostly the diagnosis is made by histologic examination of resected heart valve tissue. CASE PRESENTATION: In this case report, we described a patient with a classical Whipple’s disease. Transesophageal echocardiography (TEE) showed a vegetation on noncoronary cusp of the aortic valve. Whipple’s disease was confirmed by positive Tropheryma whipplei polymerase chain reaction (PCR) in EDTA blood and a duodenal biopsy with positive periodic acid-Schiff stain (PAS) macrophages. CONCLUSION: Due to timely diagnosis, our patient was treated with antibiotics without valve replacement. BioMed Central 2012-10-30 /pmc/articles/PMC3506451/ /pubmed/23110725 http://dx.doi.org/10.1186/1756-0500-5-600 Text en Copyright ©2012 Algin et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Algin, Ahmet
Wegdam-Blans, Marjolijn
Verduin, Kees
Janssen, Hans
van Dantzig, Jan-Melle
Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment
title Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment
title_full Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment
title_fullStr Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment
title_full_unstemmed Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment
title_short Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment
title_sort tropheryma whipplei aortic valve endocarditis, cured without surgical treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506451/
https://www.ncbi.nlm.nih.gov/pubmed/23110725
http://dx.doi.org/10.1186/1756-0500-5-600
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AT janssenhans tropherymawhippleiaorticvalveendocarditiscuredwithoutsurgicaltreatment
AT vandantzigjanmelle tropherymawhippleiaorticvalveendocarditiscuredwithoutsurgicaltreatment

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