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Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice

BACKGROUND: Sirtuins are important regulators of glucose and fat metabolism, and sirtuin activation has been proposed as a therapeutic target for insulin resistance and diabetes. We have shown leucine to increase mitochondrial biogenesis and fat oxidation via Sirt1 dependent pathways. Resveratrol is...

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Detalles Bibliográficos
Autores principales:	Bruckbauer, Antje, Zemel, Michael B, Thorpe, Teresa, Akula, Murthy R, Stuckey, Alan C, Osborne, Dustin, Martin, Emily B, Kennel, Stephen, Wall, Jonathan S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506499/ https://www.ncbi.nlm.nih.gov/pubmed/22913271 http://dx.doi.org/10.1186/1743-7075-9-77

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