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Neuromuscular effects of G93A-SOD1 expression in zebrafish
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal disorder involving the degeneration and loss of motor neurons. The mechanisms of motor neuron loss in ALS are unknown and there are no effective treatments. Defects in the distal axon and at the neuromuscular junction are early events in the...
Autores principales: | Sakowski, Stacey A, Lunn, J Simon, Busta, Angela S, Oh, Sang Su, Zamora-Berridi, Grettel, Palmer, Madeline, Rosenberg, Andrew A, Philip, Stephen G, Dowling, James J, Feldman, Eva L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506515/ https://www.ncbi.nlm.nih.gov/pubmed/22938571 http://dx.doi.org/10.1186/1750-1326-7-44 |
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