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Effects of Molecular Crowding on the Dynamics of Intrinsically Disordered Proteins
Inside cells, the concentration of macromolecules can reach up to 400 g/L. In such crowded environments, proteins are expected to behave differently than in vitro. It has been shown that the stability and the folding rate of a globular protein can be altered by the excluded volume effect produced by...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506533/ https://www.ncbi.nlm.nih.gov/pubmed/23189168 http://dx.doi.org/10.1371/journal.pone.0049876 |