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Cancer Associated Aberrant Protein O-Glycosylation Can Modify Antigen Processing and Immune Response

Aberrant glycosylation of mucins and other extracellular proteins is an important event in carcinogenesis and the resulting cancer associated glycans have been suggested as targets in cancer immunotherapy. We assessed the role of O-linked GalNAc glycosylation on antigen uptake, processing, and prese...

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Detalles Bibliográficos
Autores principales: Madsen, Caroline B., Petersen, Cecilie, Lavrsen, Kirstine, Harndahl, Mikkel, Buus, Søren, Clausen, Henrik, Pedersen, Anders E., Wandall, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506546/
https://www.ncbi.nlm.nih.gov/pubmed/23189185
http://dx.doi.org/10.1371/journal.pone.0050139