Cargando…

Long-Lasting Protection of Activity of Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors (PIs) by Boosted PI Containing Regimens

BACKGROUND: The accumulation of mutations after long-lasting exposure to a failing combination antiretroviral therapy (cART) is problematic and severely reduces the options for further successful treatments. METHODS: We studied patients from the Swiss HIV Cohort Study who failed cART with nucleoside...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scherrer, Alexandra U., Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Aubert, Vincent, Furrer, Hansjakob, Calmy, Alexandra, Cavassini, Matthias, Elzi, Luigia, Vernazza, Pietro L., Bernasconi, Enos, Ledergerber, Bruno, Günthard, Huldrych F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506586/ https://www.ncbi.nlm.nih.gov/pubmed/23189194 http://dx.doi.org/10.1371/journal.pone.0050307

Ejemplares similares

Correction: Long-Lasting Protection of Activity of Nucleoside Reverse Transcriptase Inhibitors and Protease Inhibitors (PIs) by Boosted PI Containing Regimens
por: Scherrer, Alexandra U., et al.
Publicado: (2013)

Minor Protease Inhibitor Mutations at Baseline Do Not Increase the Risk for a Virological Failure in HIV-1 Subtype B Infected Patients
por: Scherrer, Alexandra U., et al.
Publicado: (2012)

Adverse events of raltegravir and dolutegravir
por: Elzi, Luigia, et al.
Publicado: (2017)

Predictors of Virological Failure and Time to Viral Suppression of First-Line Integrase Inhibitor–Based Antiretroviral Treatment
por: Pyngottu, Ashima, et al.
Publicado: (2020)

Adherence as a Predictor of the Development of Class-Specific Resistance Mutations: The Swiss HIV Cohort Study
por: von Wyl, Viktor, et al.
Publicado: (2013)

Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis
por: Turk, Teja, et al.
Publicado: (2017)

Genotypic Resistance Tests Sequences Reveal the Role of Marginalized Populations in HIV-1 Transmission in Switzerland
por: Shilaih, Mohaned, et al.
Publicado: (2016)

Increases in Condomless Sex in the Swiss HIV Cohort Study
por: Kouyos, Roger D., et al.
Publicado: (2015)

Life expectancy in HIV-positive persons in Switzerland: matched comparison with general population
por: Gueler, Aysel, et al.
Publicado: (2017)

The Individualized Genetic Barrier Predicts Treatment Response in a Large Cohort of HIV-1 Infected Patients
por: Beerenwinkel, Niko, et al.
Publicado: (2013)

Ability to Work and Employment Rates in Human Immunodeficiency Virus (HIV)-1-Infected Individuals Receiving Combination Antiretroviral Therapy: The Swiss HIV Cohort Study
por: Elzi, Luigia, et al.
Publicado: (2016)

Association of Incomplete Adherence to Antiretroviral Therapy With Cardiovascular Events and Mortality in Virologically Suppressed Persons With HIV: The Swiss HIV Cohort Study
por: Castillo-Mancilla, Jose R, et al.
Publicado: (2021)

CD4/CD8 ratio and CD8 counts predict CD4 response in HIV-1-infected drug naive and in patients on cART
por: Sauter, Rafael, et al.
Publicado: (2016)

Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study
por: Kusejko, Katharina, et al.
Publicado: (2018)

Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity
por: Bertels, Frederic, et al.
Publicado: (2018)

The Cumulative Impact of Harm Reduction on the Swiss HIV Epidemic: Cohort Study, Mathematical Model, and Phylogenetic Analysis
por: Marzel, Alex, et al.
Publicado: (2018)

A Comparison of Initial Antiretroviral Therapy in the Swiss HIV Cohort Study and the Recommendations of the International AIDS Society-USA
por: Wandeler, Gilles, et al.
Publicado: (2011)

Phylogenetic Approach Reveals That Virus Genotype Largely Determines HIV Set-Point Viral Load
por: Alizon, Samuel, et al.
Publicado: (2010)

AIDS defining opportunistic infections in patients with high CD4 counts in the combination antiretroviral therapy (cART) era: things ain't what they used to be
por: Gisler, Valentin, et al.
Publicado: (2014)

IL-4 polymorphism influences susceptibility to Pneumocystis jirovecii pneumonia in HIV-positive patients
por: Wójtowicz, Agnieszka, et al.
Publicado: (2019)

A Phylogeny-aware GWAS Framework to Correct for Heritable Pathogen Effects on Infectious Disease Traits
por: Nadeau, Sarah, et al.
Publicado: (2022)

Ambiguous Nucleotide Calls From Population-based Sequencing of HIV-1 are a Marker for Viral Diversity and the Age of Infection
por: Kouyos, Roger D., et al.
Publicado: (2011)

Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity
por: Kadelka, Claus, et al.
Publicado: (2018)

Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics
por: Kühnert, Denise, et al.
Publicado: (2018)

The Impact of Binge Drinking on Mortality and Liver Disease in the Swiss HIV Cohort Study
por: Surial, Bernard, et al.
Publicado: (2021)

Improved sensitivity of an interferon-gamma release assay (T-SPOT.TB™) in combination with tuberculin skin test for the diagnosis of latent tuberculosis in the presence of HIV co-Infection
por: Elzi, Luigia, et al.
Publicado: (2011)

Transient detectable viremia and the risk of viral rebound in patients from the Swiss HIV Cohort Study
por: Young, Jim, et al.
Publicado: (2015)

Persistence of Transmitted HIV-1 Drug Resistance Mutations Associated with Fitness Costs and Viral Genetic Backgrounds
por: Yang, Wan-Lin, et al.
Publicado: (2015)

Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART
por: Wan, Chenjie, et al.
Publicado: (2020)

Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL’HIV trial
por: Sculier, Delphine, et al.
Publicado: (2020)

Mortality from suicide among people living with HIV and the general Swiss population: 1988‐2017
por: Ruffieux, Yann, et al.
Publicado: (2019)

Similar But Different: Integrated Phylogenetic Analysis of Austrian and Swiss HIV-1 Sequences Reveal Differences in Transmission Patterns of the Local HIV-1 Epidemics
por: Kusejko, Katharina, et al.
Publicado: (2022)

Understanding the Decline of Incident, Active Tuberculosis in People With Human Immunodeficiency Virus in Switzerland
por: Zeeb, Marius, et al.
Publicado: (2023)

Rates and predictors of switching to tenofovir alafenamide-containing ART in a nationwide cohort
por: Surial, Bernard, et al.
Publicado: (2019)

Diagnosis of latent tuberculosis infection is associated with reduced HIV viral load and lower risk for opportunistic infections in people living with HIV
por: Kusejko, Katharina, et al.
Publicado: (2020)

Cohort-Derived Machine Learning Models for Individual Prediction of Chronic Kidney Disease in People Living With Human Immunodeficiency Virus: A Prospective Multicenter Cohort Study
por: Roth, Jan A, et al.
Publicado: (2020)

Impact of Previous Virological Treatment Failures and Adherence on the Outcome of Antiretroviral Therapy in 2007
por: Ballif, Marie, et al.
Publicado: (2009)

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy
por: Barceló, Catalina, et al.
Publicado: (2020)

Replicative phenotyping adds value to genotypic resistance testing in heavily pre-treated HIV-infected individuals - the Swiss HIV Cohort Study
por: Fehr, Jan, et al.
Publicado: (2011)

Low rates of nucleoside reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor drug resistance in Botswana
por: Moyo, Sikhulile, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vhf9ftclchha35b4df1e40nt5e