The AGC Kinase Inhibitor H89 Attenuates Airway Inflammation in Mouse Models of Asthma

BACKGROUND: H89 is a potent inhibitor of Protein Kinase A (PKA) and Mitogen- and Stress-Activated protein Kinase 1 (MSK1) with some inhibitory activity on other members of the AGC kinase family. H89 has been extensively used in vitro but its anti-inflammatory potential in vivo has not been reported...

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Detalles Bibliográficos
Autores principales: Reber, Laurent L., Daubeuf, François, Nemska, Simona, Frossard, Nelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506657/
https://www.ncbi.nlm.nih.gov/pubmed/23189147
http://dx.doi.org/10.1371/journal.pone.0049512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506657/
https://www.ncbi.nlm.nih.gov/pubmed/23189147
http://dx.doi.org/10.1371/journal.pone.0049512

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