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The AGC Kinase Inhibitor H89 Attenuates Airway Inflammation in Mouse Models of Asthma
BACKGROUND: H89 is a potent inhibitor of Protein Kinase A (PKA) and Mitogen- and Stress-Activated protein Kinase 1 (MSK1) with some inhibitory activity on other members of the AGC kinase family. H89 has been extensively used in vitro but its anti-inflammatory potential in vivo has not been reported...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506657/ https://www.ncbi.nlm.nih.gov/pubmed/23189147 http://dx.doi.org/10.1371/journal.pone.0049512 |