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Gene regulatory network inference: evaluation and application to ovarian cancer allows the prioritization of drug targets

BACKGROUND: Altered networks of gene regulation underlie many complex conditions, including cancer. Inferring gene regulatory networks from high-throughput microarray expression data is a fundamental but challenging task in computational systems biology and its translation to genomic medicine. Altho...

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Detalles Bibliográficos
Autores principales:	Madhamshettiwar, Piyush B, Maetschke, Stefan R, Davis, Melissa J, Reverter, Antonio, Ragan, Mark A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506907/ https://www.ncbi.nlm.nih.gov/pubmed/22548828 http://dx.doi.org/10.1186/gm340

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