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Phenotypic differences between apolipoprotein E genetic subgroups: research and clinical implications

With the recent interest in Alzheimer's disease course modification and earlier, even preclinical, intervention, questions have arisen regarding the potentially confounding impact of apolipoprotein E (APOE) genotype on study design, therapeutic outcomes, and even clinical practice. APOE e4 carr...

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Detalles Bibliográficos
Autor principal: Caselli, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506934/
https://www.ncbi.nlm.nih.gov/pubmed/22694803
http://dx.doi.org/10.1186/alzrt123