Cargando…
Apolipoprotein E, amyloid-ß clearance and therapeutic opportunities in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterised by extracellular amyloid-ß (Aß) and intraneuronal tau protein brain pathologies. The most significant risk factor for non-familial AD is the presence of the E4 isoform of the cholesterol transporter apolipoprotein...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506946/ https://www.ncbi.nlm.nih.gov/pubmed/22929359 http://dx.doi.org/10.1186/alzrt135 |