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Architecture of the HCN selectivity filter and control of cation permeation
Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) channels are similar in structure and function to voltage-gated potassium channels. Sequence similarity and functional analyses suggest that the HCN pore is potassium channel-like, consisting of a selectivity filter and an activation gate...
Autores principales: | Macri, Vincenzo, Angoli, Damiano, Accili, Eric A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506978/ https://www.ncbi.nlm.nih.gov/pubmed/23189243 http://dx.doi.org/10.1038/srep00894 |
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