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Architecture of the HCN selectivity filter and control of cation permeation

Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) channels are similar in structure and function to voltage-gated potassium channels. Sequence similarity and functional analyses suggest that the HCN pore is potassium channel-like, consisting of a selectivity filter and an activation gate...

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Detalles Bibliográficos
Autores principales: Macri, Vincenzo, Angoli, Damiano, Accili, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3506978/
https://www.ncbi.nlm.nih.gov/pubmed/23189243
http://dx.doi.org/10.1038/srep00894

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