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Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy

BACKGROUND AND OBJECTIVES: Optic neuritis (ON) and nonarteritic anterior ischemic optic neuropathy (NAION) have some overlapping clinical profiles. We evaluated the usefulness of B-scan ultrasonography in distinguishing ON from NAION by measuring diameter of the optic nerve. MATERIALS AND METHODS: C...

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Autores principales: Dehghani, Alireza, Giti, Masoomeh, Akhlaghi, Mohamad Reza, Karami, Mehdi, Salehi, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507029/
https://www.ncbi.nlm.nih.gov/pubmed/23210062
http://dx.doi.org/10.4103/2277-9175.94425
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author Dehghani, Alireza
Giti, Masoomeh
Akhlaghi, Mohamad Reza
Karami, Mehdi
Salehi, Fatemeh
author_facet Dehghani, Alireza
Giti, Masoomeh
Akhlaghi, Mohamad Reza
Karami, Mehdi
Salehi, Fatemeh
author_sort Dehghani, Alireza
collection PubMed
description BACKGROUND AND OBJECTIVES: Optic neuritis (ON) and nonarteritic anterior ischemic optic neuropathy (NAION) have some overlapping clinical profiles. We evaluated the usefulness of B-scan ultrasonography in distinguishing ON from NAION by measuring diameter of the optic nerve. MATERIALS AND METHODS: Consecutive patients with an acute noncompressive unilateral optic neuropathy with relative afferent pupillary defect and onset of visual loss during the last 2 weeks were included. Diagnosis of ON was based on age ≤ 35 years, orbital pain associated with eye movement, and no disk edema, and diagnosis of NAION was based on age ≥ 60 years, no orbital pain associated with eye movement, and presence of disk edema. Age- and gender-matched subjects without ocular disease were selected for comparison. The diameter of the optic nerve was measured by a single radiologist with B-scan ultrasonography. RESULTS: In ON patients, the mean diameter of the affected nerve was significantly larger than that of the unaffected nerve and also larger than that of the right nerve of young controls; P < 0.05. In NAION patients, however, there was no significant difference between the mean diameter of the affected nerve and of the unaffected nerve or the right nerve of elderly controls; P > 0.05. Also, the diameter of the affected nerve was significantly larger in ON than in AION patients; P < 0.05. CONCLUSION: B-scan ultrasonography is helpful in the early stages of optic neuropathy to distinguish ON from NAION in those cases for which the diagnosis is still uncertain after clinical evaluation.
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spelling pubmed-35070292012-12-03 Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy Dehghani, Alireza Giti, Masoomeh Akhlaghi, Mohamad Reza Karami, Mehdi Salehi, Fatemeh Adv Biomed Res Original Article BACKGROUND AND OBJECTIVES: Optic neuritis (ON) and nonarteritic anterior ischemic optic neuropathy (NAION) have some overlapping clinical profiles. We evaluated the usefulness of B-scan ultrasonography in distinguishing ON from NAION by measuring diameter of the optic nerve. MATERIALS AND METHODS: Consecutive patients with an acute noncompressive unilateral optic neuropathy with relative afferent pupillary defect and onset of visual loss during the last 2 weeks were included. Diagnosis of ON was based on age ≤ 35 years, orbital pain associated with eye movement, and no disk edema, and diagnosis of NAION was based on age ≥ 60 years, no orbital pain associated with eye movement, and presence of disk edema. Age- and gender-matched subjects without ocular disease were selected for comparison. The diameter of the optic nerve was measured by a single radiologist with B-scan ultrasonography. RESULTS: In ON patients, the mean diameter of the affected nerve was significantly larger than that of the unaffected nerve and also larger than that of the right nerve of young controls; P < 0.05. In NAION patients, however, there was no significant difference between the mean diameter of the affected nerve and of the unaffected nerve or the right nerve of elderly controls; P > 0.05. Also, the diameter of the affected nerve was significantly larger in ON than in AION patients; P < 0.05. CONCLUSION: B-scan ultrasonography is helpful in the early stages of optic neuropathy to distinguish ON from NAION in those cases for which the diagnosis is still uncertain after clinical evaluation. Medknow Publications & Media Pvt Ltd 2012-03-28 /pmc/articles/PMC3507029/ /pubmed/23210062 http://dx.doi.org/10.4103/2277-9175.94425 Text en Copyright: © 2012 Dehghani. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Dehghani, Alireza
Giti, Masoomeh
Akhlaghi, Mohamad Reza
Karami, Mehdi
Salehi, Fatemeh
Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy
title Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy
title_full Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy
title_fullStr Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy
title_full_unstemmed Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy
title_short Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy
title_sort ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507029/
https://www.ncbi.nlm.nih.gov/pubmed/23210062
http://dx.doi.org/10.4103/2277-9175.94425
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