The intracellular portion of GITR enhances NGF-promoted neurite growth through an inverse modulation of Erk and NF-κB signalling

NF-κB transcription factors play a key role in regulating the growth of neural processes in the developing PNS. Although several secreted proteins have been shown to activate NF-κB to inhibit the growth of developing sympathetic neurons, it is unknown how the endogenous level of NF-κB activity prese...

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Detalles Bibliográficos
Autores principales: McKelvey, Laura, Gutierrez, Humberto, Nocentini, Giuseppe, Crampton, Sean J., Davies, Alun M., Riccardi, Carlo R., O’keeffe, Gerard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507174/
https://www.ncbi.nlm.nih.gov/pubmed/23213379
http://dx.doi.org/10.1242/bio.20121024

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