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Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms
Mutations affecting the retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGRIP1) interactome cause syndromic retinal dystrophies. RPGRIP1 interacts with the retinitis pigmentosa GTPase regulator (RPGR) through a domain homologous to RCC1 (RHD), a nucleotide exchange factor of Ran GTPase...
Autores principales: | Patil, Hemangi, Guruju, Mallikarjuna R., Cho, Kyoung-in, Yi, Haiqing, Orry, Andrew, Kim, Hyesung, Ferreira, Paulo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507198/ https://www.ncbi.nlm.nih.gov/pubmed/23213406 http://dx.doi.org/10.1242/bio.2011489 |
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