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Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2
Endogenous 24-hour rhythms are generated by circadian clocks located in most tissues. The molecular clock mechanism is based on feedback loops involving clock genes and their protein products. Post-translational modifications, including ubiquitination, are important for regulating the clock feedback...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507220/ https://www.ncbi.nlm.nih.gov/pubmed/23213472 http://dx.doi.org/10.1242/bio.20121990 |