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The endocytic adapter E-Syt2 recruits the p21 GTPase activated kinase PAK1 to mediate actin dynamics and FGF signalling

Fibroblast growth factor (FGF) signalling plays an essential role in early vertebrate development. However, the response to FGF requires endocytosis of the activated FGF receptor (FGFR) that is in part dependent on remodelling of the actin cytoskeleton. Recently we showed that the extended synaptota...

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Detalles Bibliográficos
Autores principales: Jean, Steve, Tremblay, Michel G., Herdman, Chelsea, Guillou, François, Moss, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507230/
https://www.ncbi.nlm.nih.gov/pubmed/23213466
http://dx.doi.org/10.1242/bio.2012968