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Segregation of PIP2 and PIP3 into distinct nanoscale regions within the plasma membrane

PIP(2) and PIP(3) are implicated in a wide variety of cellular signaling pathways at the plasma membrane. We have used STORM imaging to localize clusters of PIP(2) and PIP(3) to distinct nanoscale regions within the plasma membrane of PC12 cells. With anti-phospholipid antibodies directly conjugated...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Richards, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507238/
https://www.ncbi.nlm.nih.gov/pubmed/23213479
http://dx.doi.org/10.1242/bio.20122071