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Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up
OBJECTIVES: To evaluate in a prospective, randomized study, the efficacy and safety profile of photoselective vaporization of prostate (PVP) using a 80W potassium titanyl phosphate (KTP) laser when compared to standard transurethral resection of prostate (TURP) in patients with lower urinary tract s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507401/ https://www.ncbi.nlm.nih.gov/pubmed/23204660 http://dx.doi.org/10.4103/0970-1591.102708 |
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author | Mohanty, Nayan K. Vasudeva, Pawan Kumar, Anup Prakash, Sanjay Jain, Manoj Arora, Rajender P. |
author_facet | Mohanty, Nayan K. Vasudeva, Pawan Kumar, Anup Prakash, Sanjay Jain, Manoj Arora, Rajender P. |
author_sort | Mohanty, Nayan K. |
collection | PubMed |
description | OBJECTIVES: To evaluate in a prospective, randomized study, the efficacy and safety profile of photoselective vaporization of prostate (PVP) using a 80W potassium titanyl phosphate (KTP) laser when compared to standard transurethral resection of prostate (TURP) in patients with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE). MATERIALS AND METHODS: Between February 2009 and August 2009, 117 patients satisfying the eligibility criteria underwent surgery [60 PVP{Group A}; 57 TURP{Group B}]. The groups were compared for functional outcome (both subjective and objective parameters), perioperative parameters and complications, with a follow up of one year. P value<0.05 was considered statistically significant. RESULTS: The baseline characteristics of the two groups were comparable. Mean age was 66.68 years and 65.74 years, mean IPSS score was 19.98 and 20.88, mean prostate volume was 44.77 cc and 49.02 cc in Group A and B, respectively. Improvements in IPSS, QOL, prostate volume, Q max and PVRU at 12 months were similar in both groups. PVP patients had longer operating time, lesser perioperative blood loss, shorter catheterization time and a higher dysuria rate when compared to TURP patients. The overall complication rate was similar in the two groups. CONCLUSIONS: In patients with LUTS due to BPE, KTP-PVP is an equally efficacious alternative to TURP with durable results at one year follow up with additional benefits of lesser perioperative blood loss, lesser transfusion requirements and a shorter catheterization time. Long term comparative data is awaited to clearly define the role of KTP-PVP in such patients. |
format | Online Article Text |
id | pubmed-3507401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-35074012012-11-30 Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up Mohanty, Nayan K. Vasudeva, Pawan Kumar, Anup Prakash, Sanjay Jain, Manoj Arora, Rajender P. Indian J Urol Original Article OBJECTIVES: To evaluate in a prospective, randomized study, the efficacy and safety profile of photoselective vaporization of prostate (PVP) using a 80W potassium titanyl phosphate (KTP) laser when compared to standard transurethral resection of prostate (TURP) in patients with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE). MATERIALS AND METHODS: Between February 2009 and August 2009, 117 patients satisfying the eligibility criteria underwent surgery [60 PVP{Group A}; 57 TURP{Group B}]. The groups were compared for functional outcome (both subjective and objective parameters), perioperative parameters and complications, with a follow up of one year. P value<0.05 was considered statistically significant. RESULTS: The baseline characteristics of the two groups were comparable. Mean age was 66.68 years and 65.74 years, mean IPSS score was 19.98 and 20.88, mean prostate volume was 44.77 cc and 49.02 cc in Group A and B, respectively. Improvements in IPSS, QOL, prostate volume, Q max and PVRU at 12 months were similar in both groups. PVP patients had longer operating time, lesser perioperative blood loss, shorter catheterization time and a higher dysuria rate when compared to TURP patients. The overall complication rate was similar in the two groups. CONCLUSIONS: In patients with LUTS due to BPE, KTP-PVP is an equally efficacious alternative to TURP with durable results at one year follow up with additional benefits of lesser perioperative blood loss, lesser transfusion requirements and a shorter catheterization time. Long term comparative data is awaited to clearly define the role of KTP-PVP in such patients. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3507401/ /pubmed/23204660 http://dx.doi.org/10.4103/0970-1591.102708 Text en Copyright: © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Mohanty, Nayan K. Vasudeva, Pawan Kumar, Anup Prakash, Sanjay Jain, Manoj Arora, Rajender P. Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up |
title | Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up |
title_full | Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up |
title_fullStr | Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up |
title_full_unstemmed | Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up |
title_short | Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up |
title_sort | photoselective vaporization of prostate vs. transurethral resection of prostate: a prospective, randomized study with one year follow-up |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507401/ https://www.ncbi.nlm.nih.gov/pubmed/23204660 http://dx.doi.org/10.4103/0970-1591.102708 |
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