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A modular cell-based biosensor using engineered genetic logic circuits to detect and integrate multiple environmental signals
Cells perceive a wide variety of cellular and environmental signals, which are often processed combinatorially to generate particular phenotypic responses. Here, we employ both single and mixed cell type populations, pre-programmed with engineered modular cell signalling and sensing circuits, as pro...
Autores principales: | Wang, Baojun, Barahona, Mauricio, Buck, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Advanced Technology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507625/ https://www.ncbi.nlm.nih.gov/pubmed/22981411 http://dx.doi.org/10.1016/j.bios.2012.08.011 |
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